I would recommend everybody do at least a few simulated drafts every year before the real thing. Not just because it helps you get a feel for where players are going, but because it helps you discover and prepare for scenarios where you need information quickly.
Say for example you reach the third round, and there are four players you like the most. Lets say LeSean McCoy is at the top of this list. You want to draft him, but you want to know who his handcuff is an how much you can trust him. It's hard to google all this information accurately, then make an informed decision in just 30 seconds. The clock is ticking.
It's very important to make sure that you are informed before the draft on all the potential handcuffs so as to not make a mistake. I learned this lesson the hard way last year, when I drafted Jamaal Charles in round 1 but then drafted Knile Davis as his handcuff instead of taking the time to verify Charles handcuff situation before the draft. Ultimately, Davis was demoted to 4th string and someone else got Charcandrick West and Spencer Ware, and reaped the rewards while I was left holding the bag when Charles went down with an MCL early in the season.
Sometimes RBs have clear handcuffs but other times the backup RB situation is murky and requires some detective work. Don't simply trust what drafting sites list as handcuffs. They listed Knile Davis as the Jamaal Charles handcuff for me last year and I lazily figured they were right. Currently most sites are still listing CJ Procise as the handcuff for Thomas Rawls, even though all us Seahawks fans know that it's almost certainly C-Mike. The handcuff list in the draft center is not especially accurate or up to date.
It's important to figure all this stuff out before the draft. Because in the moment, you won't have enough time to accurately verify and will be forced to take a bit of a stab in the dark.