I think it's a matter of time before schools stick two fingers up to the NCAA and give up the pretense of academics and just become a proper junior development league for the NFL.
Now that geography is out the window, if Ohio St or Clemson left to join the SEC, the games a bogey.
I wonder what happens with the remaining Big 12 schools. There's already chatter that USC is unhappy in the PAC 12 and its tv deal but rumors Nebraska wants to join the PAC 12.
Wouldn't shock me if the top PAC 12 and Big 10 teams either merged to form a super conference or formed their own conference in order to compete with the SEC. Like a Big 10 West coast and East coast division. Top half PAC 12- Oregon, Washington, USC, UCLA, maybe Stanford. Some of the remaining top Big 12 teams, maybe BYU and Notre Dame join an east division if they were willing. Big 10 East coast sheds the likes of Rugters. (You could adapt this for basketball for the Arizona schools etc).
Conference championship becomes the Rose bowl in this new super conference.
I imagine the smaller schools would find their level financially such as Oregon St and Washington St and the apple cup/civil war still would be a part of any non conference schedule game.