"Hitting on a QB" is rough. Now the success rate is skewed because bad organizations make bad decisions, but the numbers are daunting. Wilson is an outlier, in fact so is Brees.
Here is the reality:
The changes in the rules that favor the QB make it almost impossible for a team with an average or bad QB to compete, even if they have top tier players in other positions.
However a great QB can make a bad team better in 3 or 4 years, and great QBs usually keep their team near the top.
So you have to sell out to get a great QB. But the chances? That draft game has worse odd than a rigged ring-toss at the State Fair.
Take the top 15 QBs at the start of last year. Not in any order but:
1 - Aaron Rodgers, 2005 24th pick in 1st round (2nd)
2 - Ben R, 2004 11th pick in 1st Round (3rd)
3 - Andrew Luck, 2012 1st pick in 1st Round (1st)
4 - Tom Brady, 2000 33rd pick in 6th round (7th)
5 - Matt Ryan, 2008 3rd pick in 1st Round (1st)
6 - Philip Rivers, 2004 4th pick in 1st Round (4th)
7 - Drew Brees, 2001 1st pick in 2nd Round (2nd)
8 - Tony Romo (Wasnt he a UDFA?)
9 - Russell Wilson, 2012 12th pick in the 3rd Round (6th)
10 - Peyton Manning, 1998 1st pick in the 1st Round (1st)
11 - Cam Newton, 2011 1st pick in the 1st Round (1st)
12 - Joe Flacco, 2008 18th pick in the 1st Round (2nd)
13 - Matthew Stafford, 2009 1st pick in the 1st Round (1st)
14 - Ryan Tannehill, 2012 1st pick in the 3rd Round (3rd)
15 - Eli Manning, 2004 1st pick in the 1st Round (1st)
*Number in brackets is QB order taken in that year.
On average there are 3 selections in the 1st round of QBs. As you can see, for the most part you seem to have better odds at a top tier QB as the 1st overall pick, which you must often tank to get. But years where the #1 pick was a QB and did not turn into a top five QB include: 2010, 2009, 2007, 2005, 2003, 2002, 1999. (Leaving out Vick in 2001 and 2009 is debatable but Stafford to me is not a game-changer type). So 7 in close to 15 years having the 1st pick didn't get you the franchise QB.
That says that over an almost 20 year period, one in which 3 QBs are chosen in the 1st round and over 10 are chosen per draft, the best QBs come from: 1998, 2000, 2001, 2004, 2004, 2005, 2008, 2008, 2009, 2011, 2012, 2012, 2012.
Which shows that there are regularly 1-2 (if not three) year periods where no QBs are high quality, no matter how high the pick. And in most years, only 1 QB is coming out of the mix.
So what happens if you sell out to get the big QB because you have no chance without one?
Well unless it is 2012, 2011, 2005, 2004, 2001* (so five years in close to 15), you pretty much mortgaged everything to be barely average (* for Flacco in 2008 but I am still not sold on Ryan or Stafford, and while Brady came in 2000 nobody was going to pick him with the 1st pick period. Anyone with the 1st pick misses him unless they are psychic)
Qbs 2014 ? Carr, Bortles, Bridgewater
2013 Glennon
2012 Luck, Wilson (Cousins, Osweiler)
2011 Cam Newton
2010 ?
2009 Stafford
2008 Ryan, Flacco
2007 ?
2006 Cutler
2005 Smith, Rodgers
2004 Ben, Eli, Rivers, Schaub
2003 ?
2002 ?
2001 Vick, Brees
2000 Tom Brady
This means 2/3 of the time - selling out to get the great QB results in very little benefit.
All I can say is good luck LA, you will need it.
(ALSO: Looking at the #s makes it really clear just how amazing the Wilson find was, since only Brady, Brees and Wilson did something special as non-1st round picks in the recent near 20 year period. )