People are underestimating the 49ers.
They look clearly like the class of the NFL and this SB is likely 49ers vs Broncos.
SF has looked like it was stumbling a bit in two games, latter half of the Cowboys (which they dominated otherwise) and recently against the Eagles. They did lose to the Bears, and that is really the only bad game they have.
Of course it turns out the Cowboys were better than us and the Eagles went and shellacked the Giants (which looked to be on an upswing before that game).
They probably end up sleepwalking through the Rams but handle them. The 49ers are deeper and better than year's past. The WRs are good across the board and the weaknesses in the secondary have been helped by bringing in a guy from our PS (Cox). They don't have the glaring gaps they did in years past.
I am predicting the 49ers go all the way this year but get screwed by the NFL's quest to get Manning another ring in time.