I went 'No" for a few reasons.
I know the OL is unsettled, and we had turn over and we're starting new guys (basically 2 rookies). It was unsettled last year as well. Thing is, we have a game plan for if the OL is terrible; we spread the field and throw it, using quicker passes and running out of spread sets. It was very effective to say the least. If our OL starts out weak, we won't have to wait until the bye week to switch up game plans.
Our schedule is the opposite of last year. Last year, we had all the toughest games and defenses front loaded. It gave a new(er) OL no real chance to get settled and get some game reps against league average opposition. This year, our tougher games look to be at the end of the year, and we don't face any real tough defenses in the first quarter of the year (last I looked). This will allow our OL to gel a bit and get on track for the last half of the year.
Our skill positions have never really looked better. No, we don't have a RB the caliber of Lynch, but the team of Rawls, Prosise, Michael and Collins will be very effective. This doesn't even count on all of our rookies to have unreasonable seasons. It also doesn't count on Rawls having to be healthy.
On the outside, we have Baldwin, Lockett, and Kearse. Kearse is a clutch WR, Baldwin made huge strides last year, and it stands to reason that Lockett can improve. Baldwin and Lockett were both top 10 in the NFL in catch rate. Another year of Wilson is going to make them better.
Wilson showed he can carry the team with additional reps, while not turning the ball over behind a terrible OL. Pete's philosophy is run heavy ball control, but he's never said he's been married to having to start out the game that way. As a matter of fact, he likes to pass it, but he just wants to close the game out on the ground in the 4th quarter (a paraphrase, but it IS a quote from him).
We have a lot more reasons we'll be status quo or (I think) better, than we have reasons we'll regress.